Pharmacies Open Now in Johannesburg: 24-Hour and Extended-Hours Guide

Finding an open pharmacy when an urgent medical need arises in Johannesburg—whether it is a late-night fever, an unexpected allergic reaction, or an emergency prescription refill—can be stressful. While most retail dispensaries follow standard shopping mall hours, several 24-hour pharmacies, late-night drugstores, and hospital dispensaries across Johannesburg operate around the clock or well into the evening.

This comprehensive guide outlines the best options for finding open pharmacies across Greater Johannesburg, including 24/7 locations, extended-hour facilities, hospital dispensaries, and key regional operating hours.

24-Hour Pharmacies in Johannesburg

For late-night or early-morning emergencies, these pharmacies operate 24 hours a day, 7 days a week, including public holidays.

Pharmacy Name	Area / Suburb	Address	Contact Number	Key Services
Bellevue Pharmacy	Yeoville	63A Raleigh St, Yeoville, Johannesburg	+27 11 720 7175	24/7 Dispensary, Emergency OTC, Prescription Refills
Gift Pharmacy	Newtown (CBD)	28 Plein St, Newtown, Johannesburg	+27 11 333 0188	24/7 Dispensary, General Health Supplies
Netcare Linksfield Hospital Pharmacy	Orange Grove / Linksfield	24 12th Ave, Orange Grove, Johannesburg	+27 11 647 3600	Emergency Hospital Dispensary, Critical Care Meds
Netcare Olivedale Hospital Pharmacy	Randburg / Olivedale	Cnr President Fouche & Windsor Way, Olivedale	+27 11 777 2000	24-Hour Hospital Pharmacy, Prescription Medication
Netcare Mulbarton Hospital Pharmacy	Mulbarton (Joburg South)	25 True North Rd, Mulbarton, Johannesburg	+27 11 682 4323	Hospital Dispensary, Emergency Medication

Late-Night & Extended-Hours Pharmacies

If you need medication after typical retail closing times (between 5:00 PM and 6:00 PM) but before midnight, several suburban pharmacies offer extended evening trading hours:

Sandton & Northern Suburbs

• Morningside Dispensary (Morningside, Sandton)
  • Trading Hours: 7:00 AM – 9:00 PM (Mon–Fri) | 8:30 AM – 9:00 PM (Sat–Sun & Public Holidays)
  • Address: The Wedge Shopping Centre, 255 Rivonia Rd, Morningside
  • Phone: +27 11 883 6588
  • Highlights: On-site wellness clinic, IV lounge, robotic dispensing system, and prescription delivery within 5 km.
• Keyalena Pharmacy (Fourways)
  • Trading Hours: 9:00 AM – 9:00 PM (Mon–Sat) | 10:00 AM – 8:00 PM (Sun)
  • Address: Fourways Gardens Shopping Centre, Uranium St, Fourways
  • Phone: +27 11 465 6062
• Life Fourways Hospital Pharmacy (Fourways)
  • Trading Hours: Open until 10:00 PM daily
  • Address: Cnr Cedar Rd & Cedar Rd West, Fourways
  • Phone: +27 11 875 1289

Johannesburg Central, Inner City & East

• Hillbrow Pharmacy & Medicine (Hillbrow)
  • Trading Hours: 9:00 AM – 11:00 PM daily
  • Address: 52A Pretoria St, Hillbrow
  • Phone: +27 11 642 6936
• Rapha Pharmacy (Yeoville)
  • Trading Hours: 7:30 AM – 9:00 PM daily
  • Address: 45 Raleigh St, Yeoville
  • Phone: +27 11 648 2425
• Clicks Pharmacy – Netcare Milpark (Parktown West)
  • Trading Hours: 8:30 AM – 9:00 PM (Mon–Fri) | Closes at 5:00 PM on Public Holidays
  • Address: 9 Guild Rd, Parktown West
  • Phone: +27 11 480 5698
• Batho Care Pharmacy (Bramley)
  • Trading Hours: 8:00 AM – 8:00 PM daily
  • Address: 274 Corlett Dr, Bramley
  • Phone: +27 11 346 5594

West Rand & Southern Suburbs

• Medix Pharmacy (Florida, Roodepoort)
  • Trading Hours: 8:00 AM – 9:00 PM daily
  • Address: 8 Goldman St, Florida, Roodepoort
  • Phone: +27 11 672 0590
• Taurus Pharmacy (Mulbarton)
  • Trading Hours: 8:00 AM – 8:00 PM daily
  • Address: Mulbarton Medi Centre, True North Rd, Mulbarton
  • Phone: +27 11 432 3484

Retail Chains: Clicks, Dis-Chem & Community Outlets

Major retail pharmacy chains across Johannesburg follow standard trading patterns depending on whether they are located in neighborhood centers or major regional shopping malls:

Dis-Chem Pharmacies

• Regional Malls (Sandton City, Cresta, Rosebank Mall, Mall of Africa, Eastgate): Typically open from 8:00 AM or 9:00 AM until 6:00 PM or 7:00 PM on weekdays, with early closing on Sundays (usually 5:00 PM).
• Stand-Alone Stores & Medical Centers: Hours generally align with local clinic and shopping center schedules.
• Services: Full dispensaries, primary care clinics, chronic medication collection, and online prescription uploading for instore pickup.

Clicks Pharmacies

• Standard Outlets: Usually trade between 8:00 AM and 6:00 PM weekdays, and 8:00 AM to 5:00 PM on Saturdays and Sundays.
• Hospital-Based Branches: Outlets co-located with private hospitals (such as Netcare Milpark) operate extended hours up to 9:00 PM.

Independent & Franchise Pharmacies

• Chains like The Local Choice and Ringpharm, alongside long-standing independent establishments (such as Ackermans Pharmacy in Germiston/East Rand), offer localized primary health services, baby clinics, and specialized dispensaries.

Tips for Visiting a Pharmacy After Hours in Johannesburg

1. Call Ahead: Operating hours—especially during public holidays or emergency maintenance—can fluctuate. Always call the pharmacy directly before traveling late at night to confirm staff availability and script-dispensing services.
2. Bring Valid Identification & Prescriptions: If filling Schedule 3 or higher prescription medication, ensure you have a physical or valid digital doctor’s prescription alongside your South African ID or passport and medical aid card.
3. Emergency Hospital Outlets: If retail options are closed, private hospital emergency units (Netcare, Life Healthcare, and Mediclinic facilities) have dispensaries or casualty units capable of supplying emergency medication.
4. Safety Precautions: When visiting late-night street-facing dispensaries or inner-city locations after dark, practice standard safety measures: park in well-lit designated parking areas and avoid leaving valuables visible inside your vehicle.