Pharmacies Open Today in Johannesburg: 24-Hour & Late-Night Guide
Navigating health needs after hours or during weekends requires quick access to reliable medication and expert advice. Whether you need an emergency prescription filled in the middle of the night, over-the-counter medication on a Sunday, or advice from a pharmacist after standard business hours, Johannesburg offers a wide selection of 24-hour and extended-hours pharmacies across the metro region.
This guide details the operating hours, locations, and contact details for pharmacies open today in Johannesburg, covering 24/7 facilities, late-night dispensaries, and major retail pharmacy chains.
24-Hour Pharmacies in Johannesburg
For urgent medical needs requiring immediate access to prescription medicine or emergency healthcare supplies, several pharmacies across Johannesburg trade 24 hours a day, 7 days a week, including public holidays.
| Pharmacy Name | Suburb / Area | Trading Hours | Contact Number | Address |
| Bellevue Pharmacy | Yeoville | 24 Hours | 011 720 7175 | 63A Raleigh St, Yeoville, Johannesburg |
| Gift Pharmacy | Newtown | 24 Hours | 011 333 0188 | 28 Plein St, Newtown, Johannesburg |
| Linksfield Park Clinic Pharmacy | Linksfield / Orange Grove | 24 Hours | 011 647 3600 | Netcare Linksfield Hospital, 24 12th Ave, Linksfield West |
| Netcare Olivedale Pharmacy | Olivedale / Randburg | 24 Hours | 011 777 2000 | Netcare Olivedale Hospital, Cnr President Fouche & Windsor Way |
| Netcare Mulbarton Pharmacy | Mulbarton / Joburg South | 24 Hours | 011 682 4323 | Netcare Mulbarton Hospital, 25 True North Rd, Mulbarton |
| Pick n Pay Pharmacy Southgate | Southgate | 24 Hours | 011 941 2457 | Southgate Shopping Centre, Rifle Range Rd, Johannesburg South |
Late-Night & Extended Hours Pharmacies
If you require a pharmacy open past standard retail closing times (17:00 to 18:00), numerous dispensaries across Johannesburg remain open until 20:00, 21:00, or 23:00.
Central & Northern Suburbs
- Clicks Pharmacy – Netcare Milpark Hospital (Parktown West)
- Trading Hours: 08:30 – 21:00 (Mon–Fri); 08:30 – 17:00 (Saturdays, Sundays & Public Holidays)
- Contact: 011 480 5698
- Address: 9 Guild Road, Parktown West, Johannesburg
- Hillbrow Pharmacy & Medicine (Hillbrow)
- Trading Hours: 09:00 – 23:00 Daily
- Contact: 011 642 6936
- Address: 52A Pretoria Street, Hillbrow, Johannesburg
- Rapha Pharmacy (Yeoville)
- Trading Hours: 07:30 – 21:00 Daily
- Contact: 011 648 2425
- Address: 45 Raleigh Street, Yeoville, Johannesburg
Sandton, Fourways & Randburg
- Life Fourways Hospital Pharmacy (Fourways)
- Trading Hours: 09:00 – 22:00 Daily
- Contact: 011 875 1289
- Address: Cnr Cedar Road & Cedar Road West, Fourways, Sandton
- Keyalena Pharmacy (Fourways)
- Trading Hours: 09:00 – 21:00 (Mon–Sat); 10:00 – 20:00 (Sundays)
- Contact: 011 465 6062
- Address: Fourways Gardens Shopping Centre, Uranium Street, Fourways
- Morningside Dispensary (Sandton)
- Trading Hours: 07:00 – 21:00 (Mon–Fri); 08:30 – 21:00 (Weekends)
- Contact: 011 883 6588
- Address: The Wedge Shopping Centre, 255 Rivonia Road, Morningside, Sandton
Western Suburbs & Roodepoort
- Medix Pharmacy (Florida / Roodepoort)
- Trading Hours: 08:00 – 21:00 Daily
- Contact: 011 672 0590
- Address: 8 Goldman Street, Florida, Roodepoort
Eastern & Southern Suburbs
- Batho Care Pharmacy (Bramley)
- Trading Hours: 08:00 – 20:00 Daily
- Contact: 011 346 5594
- Address: 274 Corlett Drive, Bramley, Johannesburg
- Med Square Lyndhurst Pharmacy (Lyndhurst)
- Trading Hours: 08:00 – 20:00 (Mon–Fri); 08:00 – 17:00 (Weekends)
- Contact: 071 967 7925
- Address: Shop 5, Lyndhurst Road, Lyndhurst, Johannesburg
- Taurus Pharmacy (Mulbarton)
- Trading Hours: 08:00 – 20:00 Daily
- Contact: 011 432 3484
- Address: Mulbarton Medical Centre, True North Road, Mulbarton
Major Retail Pharmacy Chains in Johannesburg
For routine prescription refills, vitamins, personal care products, and wellness clinic services during standard trading hours, major retail chains operate extensively throughout Johannesburg.
Dis-Chem Pharmacies
Dis-Chem operates large-format pharmacies in major shopping centers across Greater Johannesburg, including Sandton City, Cresta Centre, Rosebank Mall, Eastgate Shopping Centre, Mall of Africa, and Clearwater Mall.
- Standard Operating Hours:
- Monday to Friday: 08:00 / 08:30 – 18:00 / 19:00
- Saturday: 08:00 – 17:00 / 18:00
- Sunday & Public Holidays: 09:00 – 15:00 / 17:00
- Services Provided: Full dispensary, primary care clinic (sister-on-duty for vaccinations, wound care, and blood pressure screening), OTC medicine, and specialized health products.
Clicks Pharmacies
Clicks has the largest network of retail dispensaries in Johannesburg, situated in neighborhood shopping centers, high-street locations, and Medicross medical centers.
- Standard Operating Hours:
- Monday to Saturday: 08:00 / 08:30 – 17:00 / 18:00 / 19:00 (depending on mall trading hours)
- Sunday & Public Holidays: 09:00 – 15:00 / 17:00
- Medicross Locations: Clicks operates dispensaries inside Medicross centers (such as Medicross Randburg, Benoni, Edenvale, Germiston, and Sophiatown), which often feature extended clinical and dispensary hours.
Alpha Pharm & Independent Community Pharmacies
Independent community pharmacies affiliated with networks like Alpha Pharm and Ringpharm provide localized care across residential suburbs like Kensington, Sandringham, Bosmont, and Rosebank.
- Standard Operating Hours: Generally 08:30 – 17:30 (Mon–Fri) and 08:30 – 13:00 (Sat). Select branches open on Sunday mornings.
Essential Tips for Visiting an Open Pharmacy in Johannesburg
- Call Ahead to Confirm Stock and Hours: Operating hours may vary on public holidays or during unexpected municipal service disruptions. Calling the dispensary directly confirms that your specific prescription item is currently in stock.
- Emergency Prescription Requirements: If visiting an emergency or 24-hour hospital pharmacy, ensure you bring a valid doctor’s prescription, a national ID or passport, and your medical aid membership card.
- Power Outages & Load Shedding: Most 24-hour hospital-attached dispensaries (Netcare, Life Healthcare, Medicross) are backed up by commercial generators, ensuring continuous refrigeration for temperature-sensitive medication (such as insulin and vaccines) and uninterrupted service.
- On-Demand Prescription Delivery: Major pharmacy chains (including Dis-Chem and Clicks) as well as delivery platforms offer express delivery services for over-the-counter medication and scheduled treatments directly to your address within major Johannesburg urban zones.